Bo-Tox is a drug made from a neurotoxin produced by the bacterium Clostridium botulinum called botulinum toxin. It is used medically to treat certain muscular conditions and cosmetically remove wrinkles by temporarily paralyzing muscles.
Botulinum toxin is predominantly used as a treatment to reduce the appearance of facial wrinkles and fine lines in older adults. Beyond aesthetic applications, Bo-Tox has been found useful in treating a variety of medical conditions including eye squints, migraines, excess sweating and leaky bladders. Botulinum toxin is currently used to treat over 20 different medical conditions, with more applications under investigation.
Injections with botulinum toxin are generally well tolerated and there are few side effects. In rare cases an individual may have a genetic predisposition that results in a mild, transient unusual response to the drug.
Around 1% of people receiving injections of botulinum toxin type A develop antibodies to the toxin that make subsequent treatments ineffective. In people treated with botulinum toxin type B for cervical dystonia, antibody development has been seen up to 44% of patients.